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PIK3R2 Antibody

PIK3R2 (Phosphatidylinositol 3-kinase, regulatory subunit 2), also called p85-Beta, is an enzyme that in humans is encoded by the PIK3R2 gene. The PIK3R2 gene is mapped on 19p13.11. Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.1-0.5 µg/mL

UniProt

O00459

Host

Rabbit

Reactivity

Human

Immunogen

Amino acids KYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQL of human PIK3R2 were used as the immunogen for the PIK3R2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the PIK3R2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This PIK3R2 antibody is available for research use only.

Storage Conditions

After reconstitution, the PIK3R2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the PIK3R2 antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) HeLa, 2) 22RV1, 3) MCF7 and 4) SW620 cell lysate with PIK3R2 antibody. Expected/observed molecular weight ~85 kDa.

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