Alpha 1 Antitrypsin Antibody

Alpha 1 Antitrypsin is secreted serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this SERPINA1 gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Rat partial recombinant protein (AA 211-411) was used as the immunogen for this Alpha 1 Antitrypsin antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the Alpha 1 Antitrypsin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Alpha 1 Antitrypsin antibody is available for research use only.

Storage Conditions

After reconstitution, the Alpha 1 Antitrypsin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the Alpha 1 Antitrypsin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Secreted, Cytoplasm/ER

Image Legend

Western blot testing of Alpha 1 Antitrypsin antibody and Lane 1: rat testis; 2: mouse testis; 3: (r) liver; 4: (m) liver lysate. Expected molecular weight: ~47 kDa (unmodified), 52 kDa (glycosylated) .