Rab3A Antibody
Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene. Synapsin I stimulated the Rab3A cycle by increasing GTP binding, GTPase activity, and Rab3A recruitment to the synaptic vesicle membrane. Conversely, Rab3A inhibited Synapsin I binding to actin and Synapsin I-induced synaptic vesicle clustering. It has been found that the protein is necessary for both forms of synaptic plasticity, and it is also involved in calcium exocytosis in neurons. In addition to that, Rab3A has been found to regulate a late step in synaptic vesicle fusion.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 192-220 (DTADPAVTGAKQGPQLSDQQVPPHQDCAC-human) were used as the immunogen for this Rab3A antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This Rab3A antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Image Legend
Western blot testing of Rab3A antibody and Lane 1: rat brain; 2: mouse brain lysate
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