LKB1 Antibody
Serine/threonine kinase 11 or LKB1 is a protein kinase which in humans is encoded by the STK11 gene. The STK11 gene, which encodes a member of the serine/threonine kinase, regulates cell polarity and functions as a tumour suppressor. STK11 is a primary upstream kinase of adenine monophosphate-activated protein kinase (AMPK), a necessary element in cell metabolism that is required for maintaining energy homeostasis. It has been found that LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human
Immunogen
Human partial recombinant protein (AA 62-430) was used as the immunogen for this LKB1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
The lyophilized LKB1 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freeze/thaws.
Limitations
This LKB1 antibody is available for research use only.
Storage Conditions
The lyophilized LKB1 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Variations in secondary/substrate sensitivities and test protocols may require the LKB1 antibody to be titrated for optimal performance.
Image Legend
Western blot testing of LKB1 antibody and human samples 1: 293T; 2: HT1080; 3: SHG-44; 4: Jurkat; 5: placenta; Predicted molecular weight: 50~60 kDa
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Arabidopsis thaliana Protein BEARSKIN1 (BRN2)
Recombinant Arabidopsis thaliana Protein BEARSKIN1 (BRN2)
Recombinant Arabidopsis thaliana Protein BEARSKIN1 (BRN2)
Recombinant Arabidopsis thaliana Protein BEARSKIN1 (BRN2)
Recombinant Arabidopsis thaliana Protein BEARSKIN1 (BRN2)