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Integrin beta 1 Antibody / ITGB1 / CD29

Integrin beta-1, also known as CD29, is a protein that in humans is encoded by the ITGB1 gene. It is an integrin unit associated with very late antigen receptors. It is known to conjoin with the alpha-3 subunit to create alpha3beta1 complex that reacts to such molecules as netrin-1 and reelin. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. The protein encoded by this gene is a beta subunit.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL

Host

Rabbit

Reactivity

Human

Immunogen

Human partial recombinant protein (AA 527-728) was used as the immunogen for this Integrin beta 1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the Integrin beta 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Integrin beta 1 antibody is available for research use only.

Storage Conditions

After reconstitution, the Integrin beta 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the Integrin beta 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cell membrane, cytoplasm

Image Legend

Western blot testing of Integrin beta 1 antibody and HeLa lysate; Predicted molecular weight: 88/130~150 kDa (unmodified/glycosylated) .

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