Bid Antibody / BH3-Interacting Domain Death Agonist
Bid (BH3-Interacting Domain Death Agonist), is a pro-apoptotic member of the Bcl-2 protein family. The BCL2 family of proteins consists of both antagonists and agonists that regulate apoptosis and compete through dimerization. By fluorescence in situ hybridization, Wang et al. (1998) mapped the human BID gene to 22q11. Luo et al. (1998) reported the purification of a cytosolic protein that induces cytochrome c release from mitochondria in response to caspase-8, the apical caspase activated by cell surface death receptors such as FAS and TNF.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL (human), IHC (FFPE) : 0.5-1 µg/mL (human; mouse; rat), Immunocytochemistry: 0.5-1 µg/mL (human)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Human partial recombinant protein (AA 1-195) was used as the immunogen for this Bid antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, ICC
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This Bid antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Location
Cytoplasmic
Image Legend
Western blot testing of Bid antibody and human samples 1: HeLa; 2: COLO320; 3: Jurkat; 4: SKOV lysate. Expected/observed molecular weight ~22 kDa.
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