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ST5 Antibody

Suppression of tumorigenicity 5 is a protein that in humans is encoded by the ST5 gene. This gene is mapped to 11p15.4. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

P78524

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

An amino acid sequence from the middle region of human ST5 (KRHSHDDMLLLAQLSL) was used as the immunogen for this ST5 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the ST5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This ST5 antibody is available for research use only.

Storage Conditions

After reconstitution, the ST5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the ST5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of ST5 antibody and Lane 1: rat testis; 2: human A431; 3: (h) HeLa; 4: (h) COLO320; 5: mouse NIH3T3 lysate. Predicted/observed molecular weight: ~126kDa.

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