CSEN Antibody
Calsenilin (CSEN) is a calcium-dependent transcriptional repressor that is highly expressed in central nervous system, thyroid gland, testis, thymus, and immune cells. The KCNIP3 gene encodes a member of the family of voltage-gated potassium(Kv) channel-interacting proteins, which belong to the neuronal calcium sensor family of proteins. Calsenilin functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. KCNIP3-regulated genes have a critical function in Ig subclass production and proliferation in B lymphocytes. It has been shown to interact with PSEN1 and PSEN2.
Product Specifications
CAS Number
9007-83-4
UniProt
Q9Y2W7
Host
Rabbit
Immunogen
An amino acid sequence from the N-terminus of human Calsenilin (MQPAKEVTKASDGSLL) was used as the immunogen for this CSEN antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Format
Antigen affinity purified
Buffer
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Reconstitution
Limitations
This CSEN antibody is available for research use only.
Frequently Asked Questions
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