TNFAIP8L3 Antibody
TNFAIP8L3 (TNF alpha-induced protein 8-like protein 3) belongs to the TNFAIP8 family. It acts as a negative mediator of apoptosis and may play a role in tumor progression. This gene suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
Q5GJ75
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human TNFAIP8L3 (RPNLKRICEGINKLLDEKVL) was used as the immunogen for this TNFAIP8L3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
Limitations
This TNFAIP8L3 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Image Legend
Western blot testing of TNFAIP8L3 antibody and Lane 1: MCF-7; 2: SW620; 3: COS7; 4: SKOV; 5: Jurkat lysate. Predicted/observed size ~33KD
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