TNFAIP8L3 Antibody

TNFAIP8L3 (TNF alpha-induced protein 8-like protein 3) belongs to the TNFAIP8 family. It acts as a negative mediator of apoptosis and may play a role in tumor progression. This gene suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL

UniProt

Q5GJ75

Host

Rabbit

Reactivity

Human

Immunogen

An amino acid sequence from the C-terminus of human TNFAIP8L3 (RPNLKRICEGINKLLDEKVL) was used as the immunogen for this TNFAIP8L3 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the TNFAIP8L3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This TNFAIP8L3 antibody is available for research use only.

Storage Conditions

After reconstitution, the TNFAIP8L3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the TNFAIP8L3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.