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CAT1 Antibody

High affinity cationic amino acid transporter 1 (CAT1), also called Solute carrier family 7 member 1 (SLC7A1) or ATRC1, is a protein that in humans is encoded by the SLC7A1 gene. This gene is mapped to 13q12.3. It acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor and plays a role in the Na+-independent y+ cationic amino acid transport system. CAT1 is a high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

P30825

Host

Rabbit

Reactivity

Human

Immunogen

An amino acid sequence from the C-terminus of human Cationic amino acid transporter 1 (LDADQARTPDGNLDQCK) was used as the immunogen for this CAT1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the CAT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This CAT1 antibody is available for research use only.

Storage Conditions

After reconstitution, the CAT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the CAT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of CAT1 antibody and Lane 1: human placenta; 2: HeLa; 3: SKOV-3; 4: HT1080 cell lysate. Expected molecular weight ~68 kDa.

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