IRAK2 Antibody
Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene. This gene is mapped to 3p25.3. Interleukin-1 receptor-associated kinase 2 is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor(IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. It binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Product Specifications
UniProt
O43187
Host
Rabbit
Immunogen
An amino acid sequence from the C-terminus of human IRAK2 (EAKRKLMENILLYKEEK) was used as the immunogen for this IRAK2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, ICC
Format
Antigen affinity purified
Buffer
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Reconstitution
Limitations
This IRAK2 antibody is available for research use only.
CAS Number
9007-83-4
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