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CBG Antibody Cortisol Binding Globulin

Corticosteroid-binding globulin (CBG), also known as Serpin A6 is a protein that in humans is encoded by the SERPINA6 gene. It is mapped 14q32.13. This gene encodes an alpha-globulin protein with corticosteroid-binding properties. CBG is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL, Immunocytochemistry: 0.5-1 µg/mL

UniProt

P08185

Host

Rabbit

Reactivity

Human

Immunogen

An amino acid sequence from the N-terminus of human Cortisol Binding Globulin (ETEIHQGFQHLHQLFAKSD) was used as the immunogen for this CBG antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, ICC

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the CBG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This CBG antibody is available for research use only.

Storage Conditions

After reconstitution, the CBG antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the CBG antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of CBG antibody and Lane 1: HeLa; 2: A431; 3: U87; 4: 22RV1; 5: PANC cell lysate. Expected/observed size ~45KD

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