Olig1 Antibody

Oligodendrocyte transcription factor 1, also known as class B basic helix-loop-helix protein 6 (BHLHB6) is a protein that in humans is encoded by the OLIG1 gene. This gene is mapped to 21q22.11. This gene is a member of the oligodendrocyte lineage gene family which encodes basic helix-loop-helix transcription factors. Studies in mice show that Olig1 is coexpressed with Olig2 in neural progenitors, and has a role in the development and maturation of oligodendrocytes. Olig1 gene promotes formation and maturation of oligodendrocytes, especially within the brain. It cooperates with Olig2 to establish the pMN domain of the embryonic neural tube.