Olig1 Antibody

Oligodendrocyte transcription factor 1, also known as class B basic helix-loop-helix protein 6 (BHLHB6) is a protein that in humans is encoded by the OLIG1 gene. This gene is mapped to 21q22.11. This gene is a member of the oligodendrocyte lineage gene family which encodes basic helix-loop-helix transcription factors. Studies in mice show that Olig1 is coexpressed with Olig2 in neural progenitors, and has a role in the development and maturation of oligodendrocytes. Olig1 gene promotes formation and maturation of oligodendrocytes, especially within the brain. It cooperates with Olig2 to establish the pMN domain of the embryonic neural tube.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

Q8TAK6

Host

Rabbit

Reactivity

Human

Immunogen

An amino acid sequence from the N-terminus of human Oligodendrocyte transcription factor 1 (ARPDAKEEQQQQLRRK) was used as the immunogen for this Olig1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the Olig1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Olig1 antibody is available for research use only.

Storage Conditions

After reconstitution, the Olig1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the Olig1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.