IRAKM Antibody
Interleukin-1 receptor-associated kinase 3, also called IRAK3 or IRAKM is an enzyme that in humans is encoded by the IRAK3 gene. The IRAKM gene consists of 12 exons spanning a region of approximately 60 kb in chromosome 12q14.3. This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q9Y616
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human IRAKM (WFPKYIVPSQDLRPYKVNID) was used as the immunogen for this IRAKM antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
Limitations
This IRAKM antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Image Legend
Western blot testing of IRAKM antibody and Lane 1: HeLa; 2: Jurkat; 3: HUT102 cell lysate. Predicted molecular weight: ~68kDa.
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