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Angiotensin Converting Enzyme Antibody (ACE)

Angiotensin converting enzyme (ACE), also called DCP or CD143 is a zinc-containing dipeptidyl carboxypeptidase widely distributed in mammalian tissues and is though to play a critical role in blood pressure regulation. This gene is mapped to 17q23.3. This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

P12821

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

An amino acid sequence from the N-terminus of human ACE (ANLPLAKRQQYNALL) was used as the immunogen for this Angiotensin Converting Enzyme antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the Angiotensin Converting Enzyme antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Angiotensin Converting Enzyme antibody is available for research use only.

Storage Conditions

After reconstitution, the Angiotensin Converting Enzyme antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the Angiotensin Converting Enzyme antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of Angiotensin Converting Enzyme antibody and Lane 1: A549; 2: HeLa; 3: 22RV1 lysate. Expected molecular weight 140-170 kDa.

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