Leupaxin Antibody

Leupaxin is a protein that in humans is encoded by the LPXN gene. This gene is mapped to 11q12.1. The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, Leupaxin may also function in, and be regulated by, tyrosine kinase activity.

Product Specifications

UniProt

O60711

Host

Rabbit

Immunogen

An amino acid sequence from the N-terminus of human Leupaxin (KKHLPDKQDHKASLD) was used as the immunogen for this Leupaxin antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Format

Antigen affinity purified

Buffer

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Reconstitution

After reconstitution, the Leupaxin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.