What is the catalog number for TIA-1 Antibody?

The catalog number for TIA-1 Antibody is R31316.

What sizes are available for TIA-1 Antibody?

TIA-1 Antibody is available in the following size(s): 100 µg.

Is TIA-1 Antibody in stock?

TIA-1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

TIA-1 Antibody

TIA-1 (T-Cell Intracellular Antigen-1), also called WDM, is an RNA-binding protein involved in splicing regulation and translational repression. It is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. By in situ hybridization, the gene is mapped to chromosome 2p13.3. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is though to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

P31483

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

An amino acid sequence from the N-terminus of human TIA1 (STQRSQDHFHVFV) was used as the immunogen for this TIA-1 antibody (100% mouse homology) .

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the TIA-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This TIA-1 antibody is available for research use only.

Storage Conditions

After reconstitution, the TIA-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the TIA-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of TIA-1 antibody and Lane 1: Jurkat; 2: Raji; 3: CEM; 4: HT1080; 5: K562 cell lysate. Predicted molecular weight: ~43kDa and ~15kDa (granulocyte-associated isoform) .