MMP12 Antibody

Matrix metalloproteinase-12, also known as MME or ME, is an enzyme that in humans is encoded by the MMP12 gene. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.2. It is though that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. This gene may involved in tissue injury and remodeling.

Product Specifications

UniProt

P39900

Host

Rabbit

Immunogen

An amino acid sequence from the C-terminus of human Matrix metalloproteinase-12 (KIDAVFYSKNKYYYFFQ) was used as the immunogen for this MMP12 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Format

Antigen affinity purified

Buffer

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Reconstitution

After reconstitution, the MMP12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.