OX40 Antibody / CD134

Tumor necrosis factor receptor superfamilymember 4 (TNR4), also known as OX40, ACT35 and CD134, is a cell surface glycoprotein. OX40 is the primary receptor for feline immunodeficiency virus. Expression can promote viral binding and renders cells permissive for viral entry, productive infection, and syncytium formation. Stimulating the receptor can improve the response to a powerful virus vector and may be useful in vaccine development.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

P43489

Host

Rabbit

Reactivity

Human

Immunogen

An amino acid sequence from the N-terminus of human CD134/OX40 (LHCVGDTYPSNDRCCHECR) was used as the immunogen for this OX40 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the OX40 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This OX40 antibody is available for research use only.

Storage Conditions

After reconstitution, the OX40 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the OX40 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic, membranous

Image Legend

Western blot testing of OX40 antibody and Lane 1: U87; 2: HeLa; 3: HT1080; 4: Jurkat; 5: COLO320; 6: MCF-7; 7: SHC; 8: COLO320; 9: SGC cell lysate. Expected molecular weight: 29-50 kDa depending on glcyosylation level.