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CCR9 Antibody

C-C chemokine receptor type 9, also called GPR-9-6 or CDw199, is a protein that in humans is encoded by the CCR9 gene. The protein encoded by this gene is a member of the beta chemoking receptor family. By radiation hybrid analysis and organization of BAC contigs by FISH on combed genomic DNA, the gene within the CCR cluster was localized at 3p21.3. It is the receptor for chemokine SCYA25/TECK. This gene subsequently transduces a signal by increasing the intracellular calcium ions level. It is an alternative coreceptor with CD4 for HIV-1 infection. CCR9 may play a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

P51686

Host

Rabbit

Reactivity

Human

Immunogen

An amino acid sequence from the N-terminus of human CCR9 (MTPTDFTSPIPNMADDY) was used as the immunogen for this CCR9 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the CCR9 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This CCR9 antibody is available for research use only.

Storage Conditions

After reconstitution, the CCR9 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Product Datasheet

https://www.nsjbio.com/tds-pdf/ccr9-antibody-r31235

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the CCR9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of CCR9 antibody and Lane 1: Jurkat; 2: HeLa; 3: SMMC-7721 cell lysate. Expected/observed size ~43KD

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