Bcl2A1 Antibody

Bcl-2-related protein A1 (BCL2A1), is the human homolog of the murine A1, and maps to chromosome 15q24.3. The BCL2A1 gene has also been referred to as BCL2L5, BFL1, and GRS. Bfl-1 protein suppresses apoptosis induced by the p53 tumor suppressor protein in a manner similar to other Bcl-2 family members such as Bcl-2, Bcl-xL and EBV-BHRF1. In addition, the bfl-I gene cooperates efficiently with the Ela oncogene in transformation of primary rodent epithelial cells. The human bfl-1 gene may play an important role in carcinogenesis.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

Q16548

Host

Rabbit

Reactivity

Human

Immunogen

An amino acid sequence from the N-terminus of human Bcl2A1 (MTDCEFGYIYRLAQDY) was used as the immunogen for this Bcl2A1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the Bcl2A1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Bcl2A1 antibody is available for research use only.

Storage Conditions

After reconstitution, the Bcl2A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Bcl2A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.