ALDH3A1 Antibody / ALDH3 / Aldehyde dehydrogenase 3

Aldehyde Dehydrogenase, Family 3, Subfamily A, Member 1, also known as ALDH3, is an enzyme that in humans is encoded by the ALDH3A1 gene. By in situ hybridization, Hiraoka et al. (1995) mapped the gene to 17p11.2. ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-4 µg/mL

UniProt

P30838

Host

Rabbit

Reactivity

Human

Immunogen

An amino acid sequence from the C-terminus of human ALDH3A1 (KVRYPPSPAKMTQH) was used as the immunogen for this ALDH3A1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2 Trehalose

Reconstitution

After reconstitution, the ALDH3A1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This ALDH3A1 antibody is available for research use only.

Storage Conditions

After reconstitution, the ALDH3A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the ALDH3A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IHC staining of FFPE human rectal cancer tissue with ALDH3A1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.