RSK1 Antibody

Ribosomal Protein S6 Kinase, 90-KD, 1, also called RSK1, is an enzyme that in humans is encoded by the RPS6KA1 gene. The RSK (ribosomal S6 kinase) family comprises growth factor-regulated serine/threonine kinases, known also as p90 (RSK) . Homologs exist in several species. By analysis of somatic cell hybrids, Moller et al. (1994) mapped the gene to chromosome 3. Bonni et al. (1999) characterized the mechanism by which the RAS-MAPK signaling pathway mediates growth factor-dependent cell survival. Inoue et al. (2007) demonstrated that p90RSK, the kinase immediately downstream from Mos-MAPK, directly targets Erp1 for CSF arrest in Xenopus oocytes.