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TRPV2 Antibody (VRL1)

Transient Receptor Potential Cation Channel Subfamily V Member 2, also known as VRL1, is a protein that, in humans, is encoded by the TRPV2 gene. The International Radiation Hybrid Mapping Consortium mapped the TRPV2 gene to chromosome 17. This gene encodes an ion channel that is activated by high temperatures above 52oC. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is though that in other tissues the channel may be activated by stimuli other than heat.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL, Immunohistochemistry (Frozen) : 0.5-1 µg/mL

UniProt

Q9Y5S1

Host

Rabbit

Reactivity

Human

Immunogen

Amino acids 42-624 (QFQGEDRKFAPQIRVNLNYRK-human) were used as the immunogen for this TRPV2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, IHC-F

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the TRPV2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This TRPV2 antibody is available for research use only.

Storage Conditions

After reconstitution, the TRPV2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the TRPV2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of TRPV2 antibody and HeLa cell lysate. Expected molecular weight: 85-95 kDa depending on glycosylation level.

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