Kallikrein-2 Antibody

Kallikrein-2, also called KLK2, is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue. It is a member of glandular kallikrein gene family that comprises 25 to 30 highly homologous genes that encode specific proteases involved in the processing of biologically active peptides. An alternative KLK2 transcript, call KLK2-linked molecule (KLM), arises from the use of an alternate donor site within intron one. KLM shares only the N-terminal 15-amino acid signal peptide with the original KLK2 protein; the mature proteins display no similarity.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

P20151

Host

Rabbit

Reactivity

Human

Immunogen

An amino acid sequence from the C-terminus of human Kallikrein-2 (243-261aa YTKVVHYRKWIKDTIAANP) was used as the immunogen for this Kallikrein-2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the Kallikrein-2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Kallikrein-2 antibody is available for research use only.

Storage Conditions

After reconstitution, the Kallikrein-2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the Kallikrein-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

Western blot testing of Kallikrein-2 antibody and Lane 1: PANC; 2: HeLa; 3: 293T cell lysate. Predicted molecular weight: 17-29 kDa (multiple isoforms) .