GST pi Antibody / GSTP1
Glutathione S-transferases pi, also known as GST3 and GSTP1, present in all tissues and cells, with the exception of red cells, in which only GSTe (erythrocyte) is observed. The gene has 7 exons and 6 introns contained within approximately 2.8 kilobases and was mapped to chromosome 11. GST pi mRNA is abundantly expressed in human skin. It does not contribute in vivo to the formation of glutathione conjugates of acetaminophen but plays a novel and unexpected role in the toxicity of this compound.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
P09211
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the N-terminus of human GST3/GST pi (RGRCAALRMLLADQGQSWKEE) was used as the immunogen for this GST pi antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
Limitations
This GST pi antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Location
Cytoplasmic, nuclear
Image Legend
Western blot testing of GST pi antibody and lysate from: 1) rat kidney; 2) human HeLa; 3) human COLO320; Predicted molecular weight ~23 kDa.
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