IL-23 Antibody (p19/alpha subunit)

Interleukin-23 is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19 (the IL-23 alpha subunit) . The International Radiation Hybrid Mapping Consortium mapped the IL-23 gene to chromosome 12. The cytokine is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration.