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FGF10 Antibody

FGF 10, Fibroblast growth factor 10, is a protein that in humans is encoded by the FGF10 gene.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF 10 contains 3 exons and spans at least 52.7 kb. By radioactive in situ hybridization, the FGF 10 gene is mapped to 5p13-p12. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts. FGF 10 translocated into urothelial cell nuclei and initiated a signaling cascade that began with the heparin-dependent tyrosine phosphorylation of surface transmembrane receptors.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

O15520

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

An amino acid sequence from the N-terminus of human FGF10 (DVRWRKLFSFTKYFLK) was used as the immunogen for this FGF10 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the FGF10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This FGF10 antibody is available for research use only.

Storage Conditions

After reconstitution, the FGF10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the FGF10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of FGF10 antibody and Lane 1: U87; 2: HeLa; 3: A549; 4: 293T; 5: HeLa cell lysate. Predicted molecular weight ~23 kDa.

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