Beta Defensin 1 Antibody / DEFB1
Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1 gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1 may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
P60022
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human beta Defensin 1 (FTKIQGTCYRGKAKCCK) was used as the immunogen for this beta Defensin 1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
Limitations
This beta Defensin 1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Location
Secreted
Image Legend
Western blot testing of Defensin 1 antibody and human COLO320 lysate; Predicted molecular weight ~7 kDa.
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