Caspase-7 Antibody

Caspase-7 is a human protein encoded by the CASP7 gene. Orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the cysteine aspartate protease family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of the protein regulates microglia activation through a protein kinase C-delta (PRKCD) -dependent pathway.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL

UniProt

P55210

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids 237-255 (RGSWFVQALCSILEEHGKD-human) were used as the immunogen for this Caspase-7 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the Caspase-7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Caspase-7 antibody is available for research use only.

Storage Conditions

After reconstitution, the Caspase-7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Caspase-7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of Caspase-7 antibody and Lane 1: HeLa; 2: MCF-7; 3: rat liver; 4: rat kidney lysate. Expected/observed molecular weight ~34 kDa (full length) .