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MDM2 Antibody

MDM2 is an important negative regulator of the p53 tumor suppressor. The protein functions both as an E3 ubiquity lipase that recognizes the N-terminal trans-activation domain(TAD) of the p53 tumor suppressor and an inhibitor of p53 transcriptional activation. Oliner et al.(1992) used MDM2 clones to localize the human gene to chromosome 12q13-q14 by analysis of human-hamster somatic cell hybrids.

Product Specifications

UniProt

Q00987

Host

Rabbit

Immunogen

Amino acids 343-358 (EKAKLENSTQAEEGFD) were used as the immunogen for this MDM2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Format

Antigen affinity purified

Buffer

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Reconstitution

After reconstitution, the MDM2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This MDM2 antibody is available for research use only.

Product Datasheet

https://cdn.gentaur.com/products/800/6686063/datasheet/r30449.pdf

CAS Number

9007-83-4

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