NR1H3 Antibody (LXR alpha)
LXR (Liver X Receptor) alpha, also known as NR1H3, is a tissue-specific cofactor that permits RXRA to function as a potent 9cRA receptor with a distinct target gene specificity. It specifically interacts with RXRA in vivo to form a functional heterodimer in which RXRA is the ligand-binding subunit. Additionally, LXR activity is critical for physiologic lipid metabolism and transport.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q13133
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 375-398 (QVERLQHTYVEALHAYVSINHPHD) were used as the immunogen for this NR1H3 antibody (100% homologous in human, mouse and rat) .
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
The lyophilized NR1H3 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This NR1H3 antibody is available for research use only.
Storage Conditions
The lyophilized NR1H3 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Titration of the NR1H3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of NR1H3 antibody and Lane 1: rat liver; 2: MCF-7; 3: HeLa cell lysate
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