AChR Antibody (nicotinic)
AChR alpha, also called CHRNA, is mapped on 2q24-q32. This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. The protein-coding sequence of the human alpha subunit gene is divided into 9 exons that correspond to different structural and functional domains of the precursor molecule.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P02708
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
Store the lyophilized AChR antibody at 4oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This AChR antibody is available for research use only.
Storage Conditions
Store the lyophilized AChR antibody at 4°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Titration of the AChR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of AChR antibody and rat skeletal muscle tissue lysate
Documents
Frequently Asked Questions
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