TIMP2 Antibody
TIMP2 gene is encoded by 5 exons spanning 83 kb of genomic DNA. TIMP2 is 83 kilobase pairs (kb) long with exon-intron splicing sites located in preserved positions among the three members of the TIMP family. The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25. TIMP-2 abrogates angiogenic factor-induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition.
Product Specifications
CAS Number
9007-83-4
Specifications
IHC (FFPE) : 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL (human protein tested) ; request BSA free format for coating
UniProt
P16035
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, ELISA (protein)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
Limitations
This TIMP2 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Location
Cytoplasmic, cell surface, secreted
Image Legend
IHC-P: TIMP2 antibody testing of human breast cancer tissue. HIER: steamed with pH6 citrate buffer.
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