NMDAR2B Antibody
The N-methyl-D-aspartate receptor 2B is also called GRIN2B. The sequence of the predicted 1,484-amino acid human protein is 98% and 96% identical to the sequences of the rat and mouse proteins, respectively. The gene is located on mouse chromosome 6 between Rho and Ly49 centromerically and Glb telomerically. Overexpression of NMDAR2B in the forebrains of transgenic mice leads to enhanced activation of NMDA receptors, facilitating synaptic potentiation in response to stimulation at 10-100 Hz.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q13224
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 1307-1320 (FVDLQKEEAALAPR) were used as the immunogen for this NMDAR2B antibody (100% homologous in human, mouse and rat) .
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
Limitations
This NMDAR2B antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Image Legend
Western blot testing of NMDAR2B antibody and Lane 1: rat brain; 2: mouse brain; 3: human U87 cell lysate. Predicted molecular weight ~166kDa.
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