CD22 Antibody
CD22 is a surface glycoprotein of B lymphocytes that is rapidly phosphorylated on cytoplasmic tyrosines after antigen receptor cross-linking. CD22 is a negative regulator of antigen receptor signaling whose onset of expression at the mature B cell stage may serve to raise the antigen concentration threshold required for B cell triggering. The human CD22 gene is expressed specifically in B lymphocytes and likely has an important function in cell-cell interactions. The B cell coreceptor CD22 plays an important role in regulating signal transduction via the B cell Ag receptor.3 CD22 is located within the band region q13.1 of chromosome 19.
Product Specifications
CAS Number
9007-83-4
UniProt
P20273
Host
Rabbit
Immunogen
An amino acid sequence from the C-terminus of human CD22 (ERPQAQENVDYVILKH) was used as the immunogen for this CD22 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Format
Antigen affinity purified
Buffer
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Reconstitution
Limitations
This CD22 antibody is available for research use only.
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Lentiviral human PHRF1 sgRNA gene knockout kit - Lentiviral human PHRF1 sgRNA gene knockout kit (plasmid)
