Angiostatin K1-3 Antibody
Ang K1-3 is a proteolytic fragment of Plasminogen. It is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity (ED50=70nM) relative to kringles 1-4 (ED50 = 135nM) .
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL (human protein tested)
UniProt
P00747
Host
Rabbit
Reactivity
Human
Immunogen
Human partial recombinant protein (AA 103-352) was used as the immunogen for this Angiostatin K1-3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, ELISA (protein)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 0.025% sodium azide
Reconstitution
Limitations
This Angiostatin K1-3 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
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Frequently Asked Questions
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