Bcl-2 Antibody
Immunoreactive BCL2 protein was detected in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue. Every tumor with molecular-genetic evidence of t (14;18) translocation expressed detectable levels of the protein, regardless of whether the breakpoint was located in or at a distance from the gene. Overexpression blocks the apoptotic death of a pro-B-lymphocyte cell line.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot (recombinant protein) : 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL (human protein tested)
UniProt
P10415
Host
Rabbit
Reactivity
Human
Immunogen
Human partial recombinant protein (AA 1-211) was used as the immunogen for this Bcl-2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB (recombinant protein), ELISA (recombinant protein)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 0.025% sodium azide
Reconstitution
Limitations
This Bcl-2 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Image Legend
Western blot testing of human recombinant protein with Bcl-2 antibody at 0.5ug/ml. Predicted molecular weight ~26 kDa.
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