Mouse TNF alpha Antibody
Tumor Necrosis Factor alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It binds and functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation and has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot (recombinant protein) : 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL (mouse protein tested)
UniProt
P06804
Host
Rabbit
Reactivity
Mouse
Immunogen
Mouse partial recombinant protein (AA 80-235) was used as the immunogen for this mouse TNF alpha antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB (recombinant protein), IHC-P, ELISA (recombinant protein)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 0.025% sodium azide
Reconstitution
Limitations
This mouse TNF alpha antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Image Legend
Western blot testing of 0.5ng/lane of mouse TNFa recombinant protein with mouse TNF alpha antibody at 0.5ug/ml.
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