P16INK4a Antibody
P16 (INK4A), also known as cyclin-dependent kinase inhibitor 2A (CDKN2A), or multiple tumor suppressor 1 (MTS1) . The p16 gene (CDKN2A) was mapped to 9p21. The p16 gene encodes a negative regulator of the cell cycle. CDKN2 plays an important role during tumorigenesis or tumor progression in a significant proportion of pancreatic adenocarcinomas. Germ-line mutations in the CDKN2A tumor-suppressor gene have been linked to the development of melanoma in some families with inherited melanoma.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (Frozen) : 1-2 µg/mL--formalin or acetone fixed tissues, Immunocytochemistry: Suitable
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human p16 protein was used as the immunogen for this p16INK4a antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
DCS-50
Applications
WB, IHC-F, ICC
Purity
Ascites
Format
Ascites
Buffer
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Reconstitution
Limitations
This p16INK4a antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1X PBS
Applications Notes
Frequently Asked Questions
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