HSP25 Antibody
The heat-shock proteins (HSPs) belong to a larger group of polypeptides, the stress proteins, that are induced in various combinations in response to environmental challenges and developmental transitions. Heat-shock 27-kD protein1also knows as HSPB. Synthesis of the small (27-kD) HSP has been shown to be correlated with the acquisition of thermotolerance. HSP27 gene is mapped to 7q11.23. Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-2 µg/mL, IHC (FFPE) : 1-2 µg/mL (1), IHC (Frozen) : 1-2 µg/mL--formalin or acetone fixed tissues, Immunocytochemistry: Suitable
Host
Mouse
Reactivity
Human, Rat, Mouse, Rabbit
Immunogen
Clonality
Monoclonal
Isotype
IgG1
Clone
IAP-9
Applications
WB, IHC-P, IHC-F, ICC
Purity
Ascites
Format
Ascites
Buffer
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Reconstitution
Limitations
This HSP25 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1X PBS
Frequently Asked Questions
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