Elastin Antibody

Elastin is a major structural protein of tissues such as aorta, which must expand rapidly and recover completely. Elastin chains are cross-linked together into an extensible 3D network. It is a molecular determinant of late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle. Defects in elastin are a cause of autosomal dominant cutis laxa.

Product Specifications

CAS Number

9007-83-4

Specifications

IHC (FFPE) : 0.25-0.5 µg/mL

Host

Mouse

Reactivity

Human, Bovine

Immunogen

Bovine alpha-elastin was used as the immunogen for this Elastin antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

BA-4

Applications

IHC-P

Purity

Ascites

Format

Ascites

Buffer

0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS

Reconstitution

After reconstitution, the Elastin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Elastin antibody is available for research use only.

Storage Conditions

After reconstitution, the Elastin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1X PBS

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the Elastin antibody may be required due to differences in protocols and secondary/substrate sensitivity.