Desmin Antibody
Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. The DES gene encodes a cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball (1992) found that Desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al. (1989) localized the gene to 2q35. Mutations are responsible for idiopathic dilated cardiomyopathy.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 2 µg/mL, IHC (FFPE) : 2-4 µg/mL
Host
Mouse
Reactivity
Human, Mouse, Rat, Rabbit
Immunogen
Desmin from pig stomach was used as the immunogen for this Desmin antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
DE-U-10
Applications
WB, IHC-P
Purity
Unpurified ascites
Format
Ascites
Buffer
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Reconstitution
Limitations
This Desmin antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1X PBS
Applications Notes
Location
Cytoplasmic, membranous
Image Legend
IHC-P: Desmin antibody testing of rat heart tissue
Frequently Asked Questions
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