Sphingomyelin Synthase 2 (aa 1-79) Human Recombinant

<strong>Sphingomyelin Synthase 2 (aa 1-79) Human Recombinant</strong>_x000D_ <strong>Catalog number:</strong> B2017564_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 35.7 kDa_x000D_ <strong>Supplied as:</strong> POWDER_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Phosphatidylcholine:ceramide Cholinephosphotransferase 2, SMS2_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lou B, Liu Q, Hou J, Kabir I, Liu P, Ding T, Dong J, Mo M, Ye D, Chen Y, Bui HH, Roth K, Cao Y, Jiang XC. 2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity J Biol Chem. 2018 Nov 23;293(47):18328-18336._x000D_ 2: Wang X, Dong J, Zhao Y, Li Y, Wu M. Adenovirus-mediated sphingomyelin synthase 2 increases atherosclerotic lesions in ApoE KO mice Lipids Health Dis. 2011 Jan 17;10:7._x000D_ 3: Li Y, Dong J, Ding T, Kuo MS, Cao G, Jiang XC, Li Z. Sphingomyelin synthase 2 activity and liver steatosis: an effect of ceramide-mediated peroxisome proliferator-activated receptor γ2 suppression Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1513-20._x000D_ 4: Zhao YR, Dong JB, Li Y, Wu MP. Sphingomyelin synthase 2 over-expression induces expression of aortic inflammatory biomarkers and decreases circulating EPCs in ApoE KO mice Life Sci. 2012 Jun 6;90(21-22):867-73._x000D_ 5: Albi E, La Porta CA, Cataldi S, Magni MV. Nuclear sphingomyelin-synthase and protein kinase C delta in melanoma cells Arch Biochem Biophys. 2005 Jun 15;438(2):156-61._x000D_ 6: Dong J, Liu J, Lou B, Li Z, Ye X, Wu M, Jiang XC. Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice J Lipid Res. 2006 Jun;47(6):1307-14._x000D_ 7: Lee WK, Torchalski B, Kohistani N, Thévenod F. ABCB1 protects kidney proximal tubule cells against cadmium-induced apoptosis: roles of cadmium and ceramide transport Toxicol Sci. 2011 Jun;121(2):343-56._x000D_ 8: Luberto C, Hannun YA. Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C? J Biol Chem. 1998 Jun 5;273(23):14550-9._x000D_ 9: Chandran S, Machamer CE. Inactivation of ceramide transfer protein during pro-apoptotic stress by Golgi disassembly and caspase cleavage Biochem J. 2012 Mar 1;442(2):391-401._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/12538495">10: Itoh M, Kitano T, Watanabe M, Kondo T, Yabu T, Taguchi Y, Iwai K, Tashima M, Uchiyama T, Okazaki T. Possible role of ceramide as an indicator of chemoresistance: decrease of the ceramide content via activation of glucosylceramide synthase and sphingomyelin synthase in chemoresistant leukemia Clin Cancer Res. 2003 Jan;9(1):415-23.</a>_x000D_ _x000D_ <strong>Products Related to Sphingomyelin Synthase 2 (aa 1-79) Human Recombinant can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>