Cathepsin D Antibody / CTSD
Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Cathepsin D is mapped to chromosome 11. The amino acid sequence predicted from the cDNA sequence shows that human cathepsin D consists of 412 amino acids with 20 and 44 amino acids in a pre- and a prosegment, respectively.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL
Host
Mouse
Reactivity
Human
Immunogen
Human liver cathepsin D was used as the immunogen for this Cathepsin D antibody.
Clonality
Monoclonal
Isotype
IgG2a
Clone
CP-D13
Applications
WB, IHC-P
Purity
Ascites
Format
Ascites
Buffer
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Reconstitution
After reconstitution, the Cathepsin D antibody can be stored at 4oC to -20oC. For long-term, aliquot and store at -20oC. Avoid repeated freeze/thaws.
Limitations
This Cathepsin D antibody is available for research use only.
Storage Conditions
After reconstitution, the Cathepsin D antibody can be stored at 4°C to -20°C. For long-term, aliquot and store at -20°C. Avoid repeated freeze/thaws.
Formulation
0.5 mg/mL with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1X PBS
Applications Notes
Titration of the Cathepsin D antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
IHC testing of FFPE human intestinal cancer tissue with Cathepsin D antibody. HIER: steamed with pH6 citrate buffer, HRP-staining.
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