Caldesmon Antibody / CALD1 / CAD (smooth muscle)
Caldesmon is a potential actomyosin regulatory protein found in smooth muscle and nonmuscle cells. The predicted smooth-muscle polypeptide is 793 amino acids long. The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. Hayashi et al. (1992) demonstrated that the human CDM gene is composed of 14 exons.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.25-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
Host
Mouse
Reactivity
Human, Mouse, Rabbit
Immunogen
Human uterus smooth muscle extract was used as the immunogen for this Caldesmon antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
HHCD
Applications
WB, IHC-P
Purity
Ascites
Format
Ascites
Buffer
1X PBS
Reconstitution
Limitations
This Caldesmon antibody is available for research use only.
Storage Conditions
The Caldesmon antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
Lyophilized mouse ascites with 1% BSA and 0.01% sodium azide
Applications Notes
Location
Cytoplasmic
Image Legend
IHC testing of FFPE human breast cancer with Caldesmon antibody (clone CD-7) . HIER: steamed with pH6 citrate buffer.
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