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Caldesmon Antibody / CALD1 / CAD (smooth muscle)

Caldesmon is a potential actomyosin regulatory protein found in smooth muscle and nonmuscle cells. The predicted smooth-muscle polypeptide is 793 amino acids long. The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. Hayashi et al. (1992) demonstrated that the human CDM gene is composed of 14 exons.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.25-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL

Host

Mouse

Reactivity

Human, Mouse, Rabbit

Immunogen

Human uterus smooth muscle extract was used as the immunogen for this Caldesmon antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

HHCD

Applications

WB, IHC-P

Purity

Ascites

Format

Ascites

Buffer

1X PBS

Reconstitution

The Caldesmon antibody (smooth) can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Caldesmon antibody is available for research use only.

Storage Conditions

The Caldesmon antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

Lyophilized mouse ascites with 1% BSA and 0.01% sodium azide

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the Caldesmon antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

IHC testing of FFPE human breast cancer with Caldesmon antibody (clone CD-7) . HIER: steamed with pH6 citrate buffer.

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