RUNX3 Antibody
The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 2-4 µg/mL
Host
Mouse
Reactivity
Human
Immunogen
A RUNX3 recombinant protein fragment was used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
RNX864
Applications
WB
Purity
Protein G Affinity Chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Aliquot the RUNX3 antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.
Limitations
This RUNX3 antibody is available for research use only.
Storage Conditions
Aliquot the RUNX3 antibody and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles.
Formulation
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Provided assay concentrations are suggestions only, RUNX3 antibody titration may be required for optimal results.
Image Legend
Western blot testing of human samples with RUNX3 antibody at 2 ug/ml. Predicted molecular weight: ~44 kDa, isoforms can be observed at 42-48 kDa.
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