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RUNX3 Antibody

The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 2-4 µg/mL

Host

Mouse

Reactivity

Human

Immunogen

A RUNX3 recombinant protein fragment was used as the immunogen for this antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

RNX864

Applications

WB

Purity

Protein G Affinity Chromatography

Format

Purified

Buffer

1X PBS, pH 7.4

Reconstitution

Aliquot the RUNX3 antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.

Limitations

This RUNX3 antibody is available for research use only.

Storage Conditions

Aliquot the RUNX3 antibody and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.nsjbio.com/tds-pdf/runx3-antibody-rnx864-n1190

Formulation

0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Provided assay concentrations are suggestions only, RUNX3 antibody titration may be required for optimal results.

Image Legend

Western blot testing of human samples with RUNX3 antibody at 2 ug/ml. Predicted molecular weight: ~44 kDa, isoforms can be observed at 42-48 kDa.

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