Exportin 4 Antibody
Importins and exportins are transport receptors carrying cargo molecules into and out of the nucleus. Exportin 4 is a member of the Importin B superfamily of RanGTP-binding proteins. Its homology to other family members is restricted to its N-terminal RanGTP-binding motif. Exportin 4 is a nuclear export receptor for eIF-5A, a protein involved in the cellular stress response, functioning as a regulator of p53-mediated and TNF-alpha-mediated apoptosis.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-3 µg/mL
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant protein fragment from the C-terminal portion of Exportin 4 was used as the immunogen for this antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Aliquot the Exportin 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Exportin 4 antibody is available for research use only.
Storage Conditions
Aliquot the Exportin 4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Image Legend
Western blot testing of human samples with Exportin 4 antibody at 1ug/ml.
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